Alzheimer’s Disease and Homeopathy
December 31st, 2006Alzheimer’s is the common form of senile dementia, a group of condition that gradually destroys brain cells. As a result it destroys memory and impairs cognitive power. This disease has a long duration and may continue for 3 years to 20 years. It gradually unfolds its mischief through gradual extension of amyloid degeneration of neural tissue of brain from neocortex, limbic system and brain stem. The degenerative process is noted as tangles and plaques on autopsy.
The neuronal functions and communications of brain system are so complicated and ambiguous that Penfield described as ‘pinnacle hidden in eternal clouds’ the foothill of which neurophysiologists are trying to clear.* The pathology alters and disrupts the dynamics of interneuronal, intra and inter-cortical, communications and decision making processes.
Cause of Alzheimer’s disease:
Cause of Alzheimer’s Disease (AD) is really not known as also the specific dynamics of its physio-pathology. As usual the health business industry is in search of some new protein as the cause of AD. That effort lead to the suggestion that a small percentage of cases is known to caused by inherited mutant genes but failed to assure what role genetics play in AD. It is suspected that this mutant gene may be responsible for early-onset familial AD at age of 30 – 60 yrs.
In other cases variants of specific genes are suspected to increases the risk of AD. Risk factor genes interact with each other and with non-genetic factors to increase risk for AD. The only risk factor gene identified so far produces ‘Apolipoprotein E’ (APOE), the normal cholesterol carrying protein. It is suggested that abnormality of this protein induces AD in 15% of cases. It may also be noted in paradox that people who inherit such variants from both parents still may not get the disease.
Other risk factors which might contribute towards AD:
Anomaly of cranial vascular system (ischemia); Brain tumor
Risk factors of heart diseases & stroke: Hypertension, High cholesterol level, low level of Folic acid and Cyanocobalamine.
Thyroid deficiency. Depression and imbalance in neuroendocrine system.
Drug Reaction
Heavy metal toxicity.
Physical, mental and social activities may retard onset and progress of AD.
Complicating factors:
Degenerative diseases like Diabetes, Gout, and Rheumatism are often associated with AD. In many cases AD appears in persons already affected with these diseases. The two together are likely to accelerate the degenerative process. Autoimmune responses of neroglial cells- possible?
Diagnosis and Prognosis of AD:
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Prognosis of this disease is said to be unfavorable under conventional allopathic therapeutic management. A person with AD lives about 8 – 25 years after initial diagnosis. Untreated cases progresses faster.
There are no specific test to confirm AD apart from brain autopsy on death. MRI may help in certain level of understanding. Thyroid function testing may hint at indirectly.
So Diagnosis mainly stands on clinical symptoms exhibited by the patient. Cognitive base line creation is important and used as benchmark for confirmation, its nature and decline as also measuring effectiveness of therapies. Based on symptoms the disease has been divided under three stages:
Early/Mild Alzheimer’s (2 – 4 years):
·       Mild forgetfulness; confusion with senile memory changes. Loss of recent memories. Difficult managing routine task such as finances and planning.
·       Impaired initiative ness and impaired spontaneity.
·       Depression and terror symptoms.
·       Still able to do most motor activities.
Mid/Moderate Alzheimer’s (2 – 10 years):
·       Loss of distant memories; impaired activities of daily living like brushing tooth, combing hair. Increasing disorientation; deficit in intellect and judgment, inability to think abstractly.
·       Behavioral symptoms: Agitation, paranoia, delusion and hallucination
·       Convulsive seizures
Late/Severe Alzheimer’s (1 – 3 years)
·       More difficulty with essential ADL
·       Total disorientation; scream, groan, refusal to eat or swallow, inappropriately cries, loses ability to communicate.
·       At greater risk to infection and pneumonia.
Therapeutic Management of AD
Conventional Allopathic system based on finding a causal organism or a protein and its annihilation is helpless at this time as specific causal protein or the gene producing this is elusive. In absence of specific drugs which alters the course of specific pathology of the disease, basic drugs for insomnia and depression are used to control the behavioral manifestations. This allows the disease to run its natural inevitability.
Hahnemanian Homeopathy is based on study of drug toxicity on healthy human being and understands the dynamics of the degenerative pathology of specific drug toxicity as also the uniqueness of individual drug toxicity. Homeopaths since long before   using the nomenclature of AD recorded curing degenerative disease of nervous system including senile dementia. Homeopathy successfully cures AD by inducing similar dynamics of degenerative pathology through dose dependent toxicity of specific drug. The toxicity produced by the drug soon spends up its force due to minuteness of the dose, liberating the system from natural disease and allowing it to re-establish normal homeostasis. Individualization of drug pathology and AD pathology is of paramount importance for therapeutic purpose. Some heavy metals, nosodes, plants and minerals are accredited with ability to cause neuro-degeneration. Medicines from this group of drugs are used as major arsenals for Homeopathic management of AD.
Matching of surface symptoms of patient with drug symptom, I guess, is of little help. Finding the ‘similimum’ of dynamics of drug pathology and disease pathology as also the constitution of drug and patient is of sure help in this treatment.
N.B.: Dr. Debdatta Chakrabarti has helped number of patients with Homeopathy.
* From Review of Medical Physiology, W.F. Ganong; Lange Medical Publication, Maruzen Company Limited, Asia Edition, 1971, p. 187